Social media users have posted pictures of poisoned stray cats inside the famous Al-Ahly Football Club.
The Chex Twitter account said 30 cats were killed in just one day.
Hossam Ghaly, an activist on Facebook, demanded that those responsible for the crime be brought to account.
Marwan Emad said this has destroyed the reputation of the club.
In August 2014, the Gezira Club in Zamalek was accused of poisioning stray cats after pictures of dead cats surfaced on social media. This resulted in a backlash by activists and human rights groups.
Edited translation from Al-Masry Al-Youm