The US State Department's number two was to meet on Wednesday with leaders of the Muslim Brotherhood's party after it claimed a crushing victory in landmark post-revolution parliamentary elections.
William Burns "will meet leaders of the Freedom and Justice Party at their headquarters in Cairo," FJP spokesperson Ahmed Sobea told AFP.
"It will be the highest level meeting with any official from the United States," Sobea said.
The Freedom and Justice Party, the Brotherhood's political arm, has claimed the lead in the final stage of legislative elections after leading throughout, the first polls since former President Hosni Mubarak was ousted in February.
Burns arrived in Egypt on Tuesday for talks with government officials, heads of political parties, activists and business leaders, a spokesperson said.
