Four people have died in a collision between two private cars on Monday at Ramses Street, near the Ghamra metro station.
Police forces and two ambulances headed to the scene of the accident to clean up the debris and transfer the dead.
A claim was filed with the incident and prosecutors were notified for investigation.
Earlier on Monday five people were killed and 12 others were injured in a collision between a microbus and a bus on Abu Simbel road, Aswan.
Egypt loses roughly 12,000 lives to traffic accidents every year. The country has a road traffic fatality rate of 42 deaths per 100,000 population, according to the World Health Organization (WHO).
Forty-eight percent of those killed are passengers of four-wheelers, though pedestrians also constitute a significant proportion at 20 percent.
According to a Central Agency for Public Mobilization and Statistics (CAPMAS) report on 2017 accidents, accidents on roads resulted in 3,747 deaths, 13,998 injuries, and 17,201 damaged vehicles.
The report adds that the main cause of accidents is the human factor, with 78.9 percent of total cases, followed by vehicle defects with 14 percent, and environmental causes (eg. road conditions) with two percent of total accidents.
Edited translation from Al-Masry Al-Youm